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What the FDA labels say about taking them together

Danazol and glipizide

Glipizide's FDA label of January 8, 2026 names danazol in its drug interactions section; the danazol label PlainMeds reads does not name glipizide. The glipizide label: “… to worsening glycemic control: atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin …”

Check it at the source: the danazol FDA label on DailyMed (effective April 30, 2020, Lannett Company, Inc.); the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited).

What does the danazol label say about glipizide?

Danazol's label (effective April 30, 2020) does not name glipizide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Danazol), Lannett Company, Inc., effective April 30, 2020 (SPL set f2c9b713-aafc-49ca-866e-334d9b5c2e2d), via openFDA; the full label on DailyMed

What does the glipizide label say about danazol?

Glipizide label, drug interactions

The following are examples of medication that may reduce the glucose-lowering effect of glipizide extended-release tablets, leading to worsening glycemic control: atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), thyroid hormones, phenytoin, nicotinic acid, and calcium channel blocking drugs.

Source: FDA drug label (Glucotrol Xl, NDA020329), Roerig, effective July 21, 2026 (SPL set eed99b60-d043-4249-9b2a-f05e46fb588d), via openFDA

Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Danazol generic labelers
31Glipizide generic labelers
DanazolGlipizide
Labeled forn/aType 2 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)$2.65 per capsule 200 mg capsule$0.0339 per tablet 5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?