What the FDA labels say about taking them together
Dabrafenib and dexamethasone
Dabrafenib's FDA label of May 20, 2026 names dexamethasone in its drug interactions section; the dexamethasone labels PlainMeds reads (4) do not name dabrafenib. The dabrafenib label: “Coadministration of TAFINLAR with other substrates of these enzymes, including dexamethasone or hormonal contraceptives, can result in decreased concentrations and loss of efficacy [see Use in Specific Populations (8.1 …”
Check it at the source: the dabrafenib FDA label on DailyMed (effective May 20, 2026, Novartis Pharmaceuticals Corporation); the dexamethasone FDA label on DailyMed (effective June 6, 2025, Hikma Pharmaceuticals USA, Inc.).
What does the dabrafenib label say about dexamethasone?
Dabrafenib label, drug interactionsCoadministration of TAFINLAR with other substrates of these enzymes, including dexamethasone or hormonal contraceptives, can result in decreased concentrations and loss of efficacy [see Use in Specific Populations (8.1, 8.
Source: FDA drug label (Tafinlar), Novartis Pharmaceuticals Corporation, effective May 20, 2026 (SPL set fee1e6b1-e1a5-4254-9f2e-a70e0f8dbdea), via openFDA; the full label on DailyMed
What does the dexamethasone label say about dabrafenib?
Dexamethasone's label (effective June 6, 2025) and its 3 other brand-application labels do not name dabrafenib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Dexamethasone Intensol), Hikma Pharmaceuticals USA, Inc., effective June 6, 2025 (SPL set b15200fb-1826-472b-a907-e677a272513b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dabrafenib | Dexamethasone | |
|---|---|---|
| Labeled for | Lung cancer | Asthma, Eczema (atopic dermatitis), Leukemia, lymphoma and myeloma, Herpes and shingles, Crohn's disease and ulcerative colitis, Multiple sclerosis, Osteoarthritis, Rheumatoid arthritis, Psoriasis, Allergies, Anemia, Pain |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.193 per tablet 4 mg tablet |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once