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What the FDA labels say about taking them together

Dabigatran and ticagrelor

Dabigatran's FDA label of June 25, 2025 names ticagrelor in its drug interactions section; the ticagrelor label PlainMeds reads does not name dabigatran. The dabigatran label: “The use of the P-gp inhibitors verapamil, amiodarone, quinidine, clarithromycin, and ticagrelor does not require a dosage adjustment of PRADAXA.”

Check it at the source: the dabigatran FDA label on DailyMed (effective June 25, 2025, Boehringer Ingelheim Pharmaceuticals Inc.); the ticagrelor FDA label on DailyMed (effective May 7, 2026, AstraZeneca Pharmaceuticals LP).

What does the dabigatran label say about ticagrelor?

Dabigatran label, drug interactions

The use of the P-gp inhibitors verapamil, amiodarone, quinidine, clarithromycin, and ticagrelor does not require a dosage adjustment of PRADAXA.

Source: FDA drug label (Pradaxa), Boehringer Ingelheim Pharmaceuticals Inc., effective June 25, 2025 (SPL set ba74e3cd-b06f-4145-b284-5fd6b84ff3c9), via openFDA; the full label on DailyMed

What does the ticagrelor label say about dabigatran?

Ticagrelor's label (effective May 7, 2026) does not name dabigatran in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (BRILINTA), AstraZeneca Pharmaceuticals LP, effective May 7, 2026 (SPL set f7b3f443-e83d-4bf2-0e96-023448fed9a8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Dabigatran generic labelers
28Ticagrelor generic labelers
DabigatranTicagrelor
Labeled forAtrial fibrillation, Blood clots (DVT and PE), Stroke preventionHeart attack and coronary artery disease, Stroke prevention
Boxed warningYesYes
Pharmacy cost (NADAC)$0.795 per capsule 150 mg capsule$0.253 per tablet 90 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?