What the FDA labels say about taking them together
Dabigatran and sugammadex
Sugammadex's FDA label of March 13, 2026 names dabigatran in its warnings and precautions section; the dabigatran labels PlainMeds reads (2) do not name sugammadex. The sugammadex label: “… unfractionated heparin, low molecular weight heparinoids, rivaroxaban, and dabigatran up to ~25% and ~50% at C max levels of sugammadex corresponding to 4 mg/kg and 16 mg/kg doses, respectively.”
Check it at the source: the dabigatran FDA label on DailyMed (effective June 25, 2025, Boehringer Ingelheim Pharmaceuticals Inc.); the sugammadex FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC).
What does the dabigatran label say about sugammadex?
Dabigatran's label (effective June 25, 2025) and its 1 other brand-application label do not name sugammadex in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pradaxa), Boehringer Ingelheim Pharmaceuticals Inc., effective June 25, 2025 (SPL set ba74e3cd-b06f-4145-b284-5fd6b84ff3c9), via openFDA; the full label on DailyMed
What does the sugammadex label say about dabigatran?
Sugammadex label, warnings and precautionsIn vitro experiments demonstrated additional aPTT and PT(INR) prolongations for sugammadex in combination with vitamin K antagonists, unfractionated heparin, low molecular weight heparinoids, rivaroxaban, and dabigatran up to ~25% and ~50% at C max levels of sugammadex corresponding to 4 mg/kg and 16 mg/kg doses, respectively.
Source: FDA drug label (BRIDION), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 5171d883-fe8f-482c-97ab-40b00975b64a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dabigatran | Sugammadex | |
|---|---|---|
| Labeled for | Atrial fibrillation, Blood clots (DVT and PE), Stroke prevention | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.795 per capsule 150 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once