What the FDA labels say about taking them together
Cyclosporine and streptomycin
Streptomycin's FDA label of January 21, 2026 names cyclosporine in its boxed warning section; the cyclosporine labels PlainMeds reads (4) do not name streptomycin.
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).
What does the cyclosporine label say about streptomycin?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the streptomycin label say about cyclosporine?
Streptomycin label, boxed warningTHE CONCURRENT OR SEQUENTIAL USE OF OTHER NEUROTOXIC AND/OR NEPHROTOXIC DRUGS WITH STREPTOMYCIN SULFATE, INCLUDING NEOMYCIN, KANAMYCIN, GENTAMICIN, CEPHALORIDINE, PAROMOMYCIN, VIOMYCIN, POLYMYXIN B, COLISTIN, TOBRAMYCIN AND CYCLOSPORINE SHOULD BE AVOIDED.
Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Streptomycin | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once