What the FDA labels say about taking them together
Cyclosporine and silodosin
Silodosin's FDA label of April 15, 2026 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name silodosin. The silodosin label: “DRUG INTERACTIONS Strong P-glycoprotein inhibitors (e.g., cyclosporine): Co-administration may increase plasma silodosin concentration.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the silodosin FDA label on DailyMed (effective April 15, 2026, Amneal Pharmaceuticals NY LLC).
What does the cyclosporine label say about silodosin?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name silodosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the silodosin label say about cyclosporine?
Silodosin label, drug interactionsDRUG INTERACTIONS Strong P-glycoprotein inhibitors (e.g., cyclosporine): Co-administration may increase plasma silodosin concentration.
Source: FDA drug label (Silodosin), Amneal Pharmaceuticals NY LLC, effective April 15, 2026 (SPL set de619e27-9384-4b86-abdc-de0557cd39e8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Silodosin | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | Enlarged prostate (BPH) |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $0.319 per capsule 8 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once