What the FDA labels say about taking them together
Cyclosporine and revefenacin
Revefenacin's FDA label of May 3, 2022 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name revefenacin. The revefenacin label: “Transporter-related drug interactions: Coadministration of YUPELRI with OATP1B1 and OATP1B3 inhibitors may lead to an increase in exposure of the active metabolite.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the revefenacin FDA label on DailyMed (effective May 3, 2022, Viatris Specialty LLC).
What does the cyclosporine label say about revefenacin?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name revefenacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the revefenacin label say about cyclosporine?
Revefenacin label, drug interactionsTransporter-related drug interactions: Coadministration of YUPELRI with OATP1B1 and OATP1B3 inhibitors (e.g. rifampicin, cyclosporine, etc.) may lead to an increase in exposure of the active metabolite.
Source: FDA drug label (YUPELRI), NDA210598 (Mylan Ireland Ltd), as published by Viatris Specialty LLC, effective May 3, 2022 (SPL set 6dfebf04-7c90-436a-9b16-750d3c1ee0a6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Revefenacin | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | COPD |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $17.43 per mL 175 mcg/3 mL solution |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once