What the FDA labels say about taking them together
Cyclosporine and pasireotide
Pasireotide's FDA label of July 16, 2024 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name pasireotide. The pasireotide label: “DRUG INTERACTIONS Drugs that Prolong QT: Use with caution in patients who are at significant risk of developing QTc prolongation Cyclosporine:”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the pasireotide FDA label on DailyMed (effective July 16, 2024, Recordati Rare Diseases, Inc.).
What does the cyclosporine label say about pasireotide?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name pasireotide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the pasireotide label say about cyclosporine?
Pasireotide label, drug interactionsConcomitant administration of cyclosporine with SIGNIFOR LAR may decrease the relative bioavailability of cyclosporine and, therefore, dose adjustment of cyclosporine to maintain therapeutic levels may be necessary.
Signifor label (Recordati Rare Diseases, Inc., February 17, 2026), drug interactionsDRUG INTERACTIONS Drugs that Prolong QT : Use with caution in patients who are at significant risk of developing QTc prolongation ( 5.3 , 7.1 ) Cyclosporine:
Source: FDA drug label (Signifor, NDA200677), Recordati Rare Diseases, Inc., effective February 17, 2026 (SPL set a09a25fc-a5a3-0c82-e053-2995a90a5d74), via openFDA
Source: FDA drug label (Signifor LAR), Recordati Rare Diseases, Inc., effective July 16, 2024 (SPL set a0aad470-3f38-af97-e053-2995a90a383a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Pasireotide | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once