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What the FDA labels say about taking them together

Cyclosporine and nifedipine

Cyclosporine's FDA label of August 10, 2026 names nifedipine in its drug interactions section; the nifedipine labels PlainMeds reads (2) do not name cyclosporine.

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the nifedipine FDA label on DailyMed (effective December 24, 2024, Aurobindo Pharma Limited).

What does the cyclosporine label say about nifedipine?

Cyclosporine label, drug interactions

The concomitant use of nifedipine should be avoided in patients in whom gingival hyperplasia develops as a side effect of cyclosporine.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the nifedipine label say about cyclosporine?

Nifedipine's label (effective December 24, 2024) and its 1 other brand-application label do not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nifedipine), Aurobindo Pharma Limited, effective December 24, 2024 (SPL set eb70b7ff-f9f0-41d0-901a-f4c04ae9ed46), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
32Nifedipine generic labelers
CyclosporineNifedipine
Labeled forOrgan transplant rejection, Rheumatoid arthritisHigh blood pressure, Angina
Boxed warningYesNo
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsion$0.130 per tablet 30 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?