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What the FDA labels say about taking them together

Cyclosporine and mycophenolic acid

Cyclosporine's FDA label of August 10, 2026 names mycophenolic acid in its drug interactions section, and mycophenolic acid's label names cyclosporine too. The cyclosporine label: “Interactions Resulting in Decrease of Other Drug Levels Cyclosporine inhibits the enterohepatic circulation of mycophenolic acid (MPA).”

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the mycophenolic acid FDA label on DailyMed (effective July 29, 2026, Novartis Pharmaceuticals Corporation).

What does the cyclosporine label say about mycophenolic acid?

Cyclosporine label, drug interactions

Interactions Resulting in Decrease of Other Drug Levels Cyclosporine inhibits the enterohepatic circulation of mycophenolic acid (MPA).

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the mycophenolic acid label say about cyclosporine?

Mycophenolic acid label, drug interactions

May decrease MPA concentrations; exercise caution when switching from cyclosporine to other drugs or from other drugs to cyclosporine. ( 7.5 ) Norfloxacin and Metronidazole:

Source: FDA drug label (Myfortic), Novartis Pharmaceuticals Corporation, effective July 29, 2026 (SPL set eed26501-890d-4ff6-88e7-6dbea4726e53), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
16Mycophenolic acid generic labelers
CyclosporineMycophenolic acid
Labeled forOrgan transplant rejection, Rheumatoid arthritisOrgan transplant rejection
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsion$0.0996 per tablet 180 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?