What the FDA labels say about taking them together
Cyclosporine and glyburide
Glyburide's FDA label of July 1, 2021 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name glyburide. The glyburide label: “Glyburide may increase cyclosporine plasma concentration and potentially lead to its increased toxicity.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the glyburide FDA label on DailyMed (effective July 1, 2021, TEVA Pharmaceuticals USA Inc).
What does the cyclosporine label say about glyburide?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name glyburide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the glyburide label say about cyclosporine?
Glyburide label, drug interactionsGlyburide may increase cyclosporine plasma concentration and potentially lead to its increased toxicity.
Source: FDA drug label (Glyburide), NDA017532 (Sanofi Aventis Us), as published by TEVA Pharmaceuticals USA Inc, effective July 1, 2021 (SPL set 50d16f1d-c814-4411-8749-62561321ecce), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Glyburide | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | Type 2 diabetes |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $0.0643 per tablet 5 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once