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What the FDA labels say about taking them together

Cyclosporine and elbasvir/grazoprevir

Elbasvir/grazoprevir's FDA label of March 13, 2026 names cyclosporine in its contraindications section; the cyclosporine labels PlainMeds reads (4) do not name elbasvir/grazoprevir.

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC).

What does the cyclosporine label say about elbasvir/grazoprevir?

Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the elbasvir/grazoprevir label say about cyclosporine?

Elbasvir/grazoprevir label, contraindications

Named in a table that the FDA label file prints without its column breaks; the full label shows the table.

Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
0Elbasvir/grazoprevir generic labelers
CyclosporineElbasvir/grazoprevir
Labeled forOrgan transplant rejection, Rheumatoid arthritisHepatitis C
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsionn/a
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?