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What the FDA labels say about taking them together

Cyclosporine and daunorubicin

Cyclosporine's FDA label of August 10, 2026 names daunorubicin in its drug interactions section; the daunorubicin labels PlainMeds reads (2) do not name cyclosporine. The cyclosporine label: “Anthracycline Antibiotics High doses of cyclosporine may increase the exposure to anthracycline antibiotics in cancer patients.”

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the daunorubicin FDA label on DailyMed (effective January 19, 2026, Hisun Pharmaceuticals USA, Inc.).

What does the cyclosporine label say about daunorubicin?

Cyclosporine label, drug interactions

Anthracycline Antibiotics High doses of cyclosporine (e.g., at starting intravenous dose of 16 mg/kg/day) may increase the exposure to anthracycline antibiotics (e.g., doxorubicin, mitoxantrone, daunorubicin) in cancer patients.

Source: FDA drug label (Sandimmune, NDA050573), Novartis Pharmaceuticals Corporation, effective July 10, 2026 (SPL set 5e5926a7-1de0-4b54-a5c0-286b6200ff82), via openFDA

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the daunorubicin label say about cyclosporine?

Daunorubicin's label (effective January 19, 2026) and its 1 other brand-application label do not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Daunorubicin Hydrochloride), Hisun Pharmaceuticals USA, Inc., effective January 19, 2026 (SPL set 9705fa12-499e-41a3-8fb4-f6df0858b851), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
2Daunorubicin generic labelers
CyclosporineDaunorubicin
Labeled forOrgan transplant rejection, Rheumatoid arthritisLeukemia, lymphoma and myeloma
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsionn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?