Skip to main content

What the FDA labels say about taking them together

Cyclosporine and danazol

Cyclosporine's FDA label of August 10, 2026 names danazol in its drug interactions section; the danazol label PlainMeds reads does not name cyclosporine. The cyclosporine label: “… erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors are known to inhibit …”

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the danazol FDA label on DailyMed (effective April 30, 2020, Lannett Company, Inc.).

What does the cyclosporine label say about danazol?

Cyclosporine label, drug interactions

Drugs That Increase Cyclosporine Concentrations Calcium Channel Blockers Antifungals Antibiotics Glucocorticoids Other Drugs diltiazem fluconazole azithromycin methylprednisolone Allopurinol nicardipine itraconazole clarithromycin Amiodarone verapamil ketoconazole erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, and saquinavir) are known to inhibit cytochrome P-450 3A and thus could potentially increase the concentrations of cyclosporine, however no formal studies of the interaction are available.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the danazol label say about cyclosporine?

Danazol's label (effective April 30, 2020) does not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Danazol), Lannett Company, Inc., effective April 30, 2020 (SPL set f2c9b713-aafc-49ca-866e-334d9b5c2e2d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
4Danazol generic labelers
CyclosporineDanazol
Labeled forOrgan transplant rejection, Rheumatoid arthritisn/a
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsion$2.65 per capsule 200 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?