What the FDA labels say about taking them together
Cyclophosphamide and daunorubicin
Daunorubicin's FDA label of January 19, 2026 names cyclophosphamide in its drug interactions section; the cyclophosphamide labels PlainMeds reads (4) do not name daunorubicin. The daunorubicin label: “Cyclophosphamide used concurrently with daunorubicin hydrochloride may also result in increased cardiotoxicity.”
Check it at the source: the cyclophosphamide FDA label on DailyMed (effective January 19, 2026, Amneal Pharmaceuticals LLC); the daunorubicin FDA label on DailyMed (effective January 19, 2026, Hisun Pharmaceuticals USA, Inc.).
What does the cyclophosphamide label say about daunorubicin?
Cyclophosphamide's label (effective January 19, 2026) and its 3 other brand-application labels do not name daunorubicin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cyclophosphamide), Amneal Pharmaceuticals LLC, effective January 19, 2026 (SPL set 520bfe39-dfd5-4a20-9a37-80078afded0d), via openFDA; the full label on DailyMed
What does the daunorubicin label say about cyclophosphamide?
Daunorubicin label, drug interactionsCyclophosphamide used concurrently with daunorubicin hydrochloride may also result in increased cardiotoxicity.
Source: FDA drug label (Daunorubicin Hydrochloride), Hisun Pharmaceuticals USA, Inc., effective January 19, 2026 (SPL set 9705fa12-499e-41a3-8fb4-f6df0858b851), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclophosphamide | Daunorubicin | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.67 per capsule 50 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once