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What the FDA labels say about taking them together

Cromolyn and histamine

Histamine's FDA label of November 3, 2025 names cromolyn in its drug interactions (prescription label) section; the cromolyn labels PlainMeds reads (2) do not name histamine. The histamine label: “Short acting steroids, inhaled beta agonists, theophylline and cromolyn do not seem to affect skin test response.”

Check it at the source: the cromolyn FDA label on DailyMed (effective February 20, 2025, Sandoz Inc); the histamine FDA label on DailyMed (effective November 3, 2025).

What does the cromolyn label say about histamine?

Cromolyn's label (effective February 20, 2025) and its 1 other brand-application label do not name histamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cromolyn Sodium), Sandoz Inc, effective February 20, 2025 (SPL set b32851c3-cd97-4be4-a09c-1deab1d6966b), via openFDA; the full label on DailyMed

What does the histamine label say about cromolyn?

Histamine label, drug interactions (prescription label)

Short acting steroids, inhaled beta agonists, theophylline and cromolyn do not seem to affect skin test response.

Source: FDA drug label (Histaminum hydrochloricum), Boiron, effective November 3, 2025 (SPL set 85b905d4-5fa3-7125-e053-2a91aa0a54f4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Cromolyn generic labelers
0Histamine generic labelers
CromolynHistamine
Labeled forAsthma, Allergiesn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.349 per mL 100 mg/5 mL oral concn/a
Shortage nowListed; availableNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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