What the FDA labels say about taking them together
Corticotropin and sodium chloride
Sodium chloride's FDA label of June 30, 2025 names corticotropin in its drug interactions section; the corticotropin labels PlainMeds reads (2) do not name sodium chloride. The sodium chloride label: “Avoid use of Sodium Chloride Injection, USP in patients receiving such products, such as corticosteroids or corticotropin.”
Check it at the source: the corticotropin FDA label on DailyMed (effective July 15, 2026, Mallinckrodt ARD LLC); the sodium chloride FDA label on DailyMed (effective June 30, 2025, Baxter Healthcare Corporation).
What does the corticotropin label say about sodium chloride?
Corticotropin's label (effective July 15, 2026) and its 1 other brand-application label do not name sodium chloride in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Acthar), Mallinckrodt ARD LLC, effective July 15, 2026 (SPL set 7b48ddec-e815-45f4-9ca0-5c0daaf56f30), via openFDA; the full label on DailyMed
What does the sodium chloride label say about corticotropin?
Sodium chloride label, drug interactionsAvoid use of Sodium Chloride Injection, USP in patients receiving such products, such as corticosteroids or corticotropin.
Sodium chloride label, warningsCertain medications, such as corticosteroids or corticotropin, may also increase risk of sodium and fluid retention, see DRUG INTERACTIONS . Avoid Sodium Chloride Injection, USP in patients with, or at risk for, hypernatremia.
Source: FDA drug label (SODIUM CHLORIDE), Baxter Healthcare Corporation, effective June 30, 2025 (SPL set 958d35f0-6834-43be-a700-fa58f38b4c19), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Corticotropin | Sodium chloride | |
|---|---|---|
| Labeled for | Multiple sclerosis, Psoriasis, Eczema (atopic dermatitis) | Cough and cold |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0887 per mL 0.9% vial |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once