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What the FDA labels say about taking them together

Colestipol and odevixibat

Odevixibat's FDA label of December 29, 2025 names colestipol in its drug interactions section; the colestipol labels PlainMeds reads (3) do not name odevixibat. The odevixibat label: “DRUG INTERACTIONS 7.1 Bile Acid Binding Resins Administer bile acid binding resins at least 4 hours before or 4 hours after administration of BYLVAY.”

Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the odevixibat FDA label on DailyMed (effective December 29, 2025, Ipsen Biopharmaceuticals, Inc.).

What does the colestipol label say about odevixibat?

Colestipol's label (effective February 19, 2024) and its 2 other brand-application labels do not name odevixibat in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed

What does the odevixibat label say about colestipol?

Odevixibat label, drug interactions

DRUG INTERACTIONS 7.1 Bile Acid Binding Resins Administer bile acid binding resins (e.g., cholestyramine, colesevelam, or colestipol) at least 4 hours before or 4 hours after administration of BYLVAY [see Dosage and Administration (2.3) ].

Source: FDA drug label (Bylvay), Ipsen Biopharmaceuticals, Inc., effective December 29, 2025 (SPL set 0935cd31-3251-4a0a-ac23-25ca4be12be9), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Colestipol generic labelers
0Odevixibat generic labelers
ColestipolOdevixibat
Labeled forHigh cholesteroln/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.658 per tablet 1 g tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?