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What the FDA labels say about taking them together

Colestipol and mycophenolate mofetil

Colestipol's FDA label of February 19, 2024 names mycophenolate mofetil in its drug interactions section; the mycophenolate mofetil labels PlainMeds reads (2) do not name colestipol. The colestipol label: “As colestipol also binds bile acids, colestipol may reduce mycophenolic acid exposure and potentially reduce efficacy of mycophenolate mofetil.”

Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the mycophenolate mofetil FDA label on DailyMed (effective August 5, 2026, Genentech, Inc.).

What does the colestipol label say about mycophenolate mofetil?

Colestipol label, drug interactions

As colestipol also binds bile acids, colestipol may reduce mycophenolic acid exposure and potentially reduce efficacy of mycophenolate mofetil.

Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed

What does the mycophenolate mofetil label say about colestipol?

Mycophenolate mofetil's label (effective August 5, 2026) and its 1 other brand-application label do not name colestipol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CellCept), NDA050722 (Roche Palo), as published by Genentech, Inc., effective August 5, 2026 (SPL set 37241e87-4af4-4dc3-a1aa-ea6f20d8dc40), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Colestipol generic labelers
36Mycophenolate mofetil generic labelers
ColestipolMycophenolate mofetil
Labeled forHigh cholesterolOrgan transplant rejection
Boxed warningNoYes
Pharmacy cost (NADAC)$0.658 per tablet 1 g tablet$0.138 per capsule 250 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?