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What the FDA labels say about taking them together

Colestipol and maralixibat

Maralixibat's FDA label of April 10, 2025 names colestipol in its drug interactions section; the colestipol labels PlainMeds reads (3) do not name maralixibat.

Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the maralixibat FDA label on DailyMed (effective April 10, 2025, Mirum Pharmaceuticals Inc.).

What does the colestipol label say about maralixibat?

Colestipol's label (effective February 19, 2024) and its 2 other brand-application labels do not name maralixibat in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed

What does the maralixibat label say about colestipol?

Maralixibat label, drug interactions

Administer LIVMARLI at least 4 hours before or 4 hours after administration of bile acid binding resins (e.g., cholestyramine, colesevelam, or colestipol).

Source: FDA drug label (Livmarli), Mirum Pharmaceuticals Inc., effective April 10, 2025 (SPL set 64000394-1ef6-4e76-8ba8-11f25ba1b167), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Colestipol generic labelers
0Maralixibat generic labelers
ColestipolMaralixibat
Labeled forHigh cholesteroln/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.658 per tablet 1 g tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?