What the FDA labels say about taking them together
Colestipol and folic acid
Folic acid's FDA label (Folic Acid) of February 11, 2026 names colestipol in its drug interactions section; the colestipol labels PlainMeds reads (3) do not name folic acid.
Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the folic acid FDA label on DailyMed (effective July 24, 2026, Rising Pharma Holdings, Inc.).
What does the colestipol label say about folic acid?
Colestipol's label (effective February 19, 2024) and its 2 other brand-application labels do not name folic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed
What does the folic acid label say about colestipol?
Folic Acid label (Ayurax, LLC, February 11, 2026), drug interactionsAdditional agents such as pentamidine, antacids, cholestyramine, colestipol, and H 2 blockers impair gastrointestinal folate uptake through pH elevation, transporter inhibition, or binding of dietary folate.
Source: FDA drug label (Folic Acid, NDA216395), Ayurax, LLC, effective February 11, 2026 (SPL set 96618bf8-6c03-4df3-9896-b7ef27ca392a), via openFDA
Source: FDA drug label (Folic Acid), Rising Pharma Holdings, Inc., effective July 24, 2026 (SPL set 0baa10dd-6d1d-4946-8236-566451132da3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Colestipol | Folic acid | |
|---|---|---|
| Labeled for | High cholesterol | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.658 per tablet 1 g tablet | $0.0201 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once