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What the FDA labels say about taking them together

Colestipol and deferasirox

Deferasirox's FDA label of January 28, 2026 names colestipol in its drug interactions section; the colestipol labels PlainMeds reads (3) do not name deferasirox. The deferasirox label: “Avoid the concomitant use of bile acid sequestrants with Exjade due to a possible decrease in deferasirox concentration.”

Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation).

What does the colestipol label say about deferasirox?

Colestipol's label (effective February 19, 2024) and its 2 other brand-application labels do not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed

What does the deferasirox label say about colestipol?

Deferasirox label, drug interactions

Avoid the concomitant use of bile acid sequestrants (e.g., cholestyramine, colesevelam, colestipol) with Exjade due to a possible decrease in deferasirox concentration.

Source: FDA drug label (Jadenu, NDA206910), Novartis Pharmaceuticals Corporation, effective December 11, 2025 (SPL set fee89140-fff1-4443-9f42-24ac004fcda1), via openFDA

Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Colestipol generic labelers
20Deferasirox generic labelers
ColestipolDeferasirox
Labeled forHigh cholesteroln/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.658 per tablet 1 g tablet$1.25 per tablet 360 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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