What the FDA labels say about taking them together
Colesevelam and deferasirox
Deferasirox's FDA label of January 28, 2026 names colesevelam in its drug interactions section; the colesevelam label PlainMeds reads does not name deferasirox. The deferasirox label: “Avoid the concomitant use of bile acid sequestrants with Exjade due to a possible decrease in deferasirox concentration.”
Check it at the source: the colesevelam FDA label on DailyMed (effective December 28, 2023, A-S Medication Solutions); the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation).
What does the colesevelam label say about deferasirox?
Colesevelam's label (effective December 28, 2023) does not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (COLESEVELAM HYDROCHLORIDE), NDA021176 (Cosette), as published by A-S Medication Solutions, effective December 28, 2023 (SPL set 0127afae-8d8d-43f2-97f9-4f99f6947e81), via openFDA; the full label on DailyMed
What does the deferasirox label say about colesevelam?
Deferasirox label, drug interactionsAvoid the concomitant use of bile acid sequestrants (e.g., cholestyramine, colesevelam, colestipol) with Exjade due to a possible decrease in deferasirox concentration.
Source: FDA drug label (Jadenu, NDA206910), Novartis Pharmaceuticals Corporation, effective December 11, 2025 (SPL set fee89140-fff1-4443-9f42-24ac004fcda1), via openFDA
Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Colesevelam | Deferasirox | |
|---|---|---|
| Labeled for | High cholesterol, Type 2 diabetes | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.262 per tablet 625 mg tablet | $1.25 per tablet 360 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once