What the FDA labels say about taking them together
Cobicistat/darunavir and pitavastatin
Cobicistat/darunavir's FDA label of February 1, 2026 names pitavastatin in its drug interactions section; the pitavastatin labels PlainMeds reads (2) do not name cobicistat/darunavir. The cobicistat/darunavir label: “For atorvastatin, fluvastatin, pitavastatin, pravastatin, and rosuvastatin, start with the lowest recommended dose and titrate while monitoring for safety (e.g. myopathy). …”
Check it at the source: the cobicistat/darunavir FDA label on DailyMed (effective February 1, 2026, Janssen Products, LP); the pitavastatin FDA label on DailyMed (effective March 31, 2026, Kowa Pharmaceuticals America, Inc.).
What does the cobicistat/darunavir label say about pitavastatin?
Cobicistat/darunavir label, drug interactionsConcomitant Drug Class/Drug Name Examples: atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin; Effect on Concentration of Darunavir, Cobicistat, or Concomitant Drug: ↑ atorvastatin ↑ fluvastatin ↑ pravastatin ↑ rosuvastatin pitavastatin: effect unknown; Clinical Comment: For atorvastatin, fluvastatin, pitavastatin, pravastatin, and rosuvastatin, start with the lowest recommended dose and titrate while monitoring for safety (e.g. myopathy). Dosage recommendations with atorvastatin or rosuvastatin are as follows: atorvastatin dosage should not exceed 20 mg/day rosuvastatin dosage should not exceed 20 mg/day
Source: FDA drug label (PREZCOBIX), Janssen Products, LP, effective February 1, 2026 (SPL set 9c38fdb6-d0ba-4f16-a0e3-85d9ec334d9f), via openFDA; the full label on DailyMed
What does the pitavastatin label say about cobicistat/darunavir?
Pitavastatin's label (effective March 31, 2026) and its 1 other brand-application label do not name cobicistat/darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Livalo), Kowa Pharmaceuticals America, Inc., effective March 31, 2026 (SPL set 44dcbf97-99ec-427c-ba50-207e0069d6d2), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cobicistat/darunavir | Pitavastatin | |
|---|---|---|
| Labeled for | HIV | High cholesterol |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $79.99 per tablet 800 mg-150 mg tablet | $0.954 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once