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What the FDA labels say about taking them together

Coal tar and cyclosporine

Cyclosporine's FDA label of August 10, 2026 names coal tar in its boxed warning section; the coal tar label PlainMeds reads does not name cyclosporine. The cyclosporine label: “For Psoriasis Patients Psoriasis patients previously treated with PUVA and to a lesser extent, methotrexate or other immunosuppressive agents, UVB, coal tar, or radiation therapy, are at an increased risk of developing …”

Check it at the source: the coal tar FDA label on DailyMed (effective December 8, 2025); the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation).

What does the coal tar label say about cyclosporine?

Coal tar's label (effective December 8, 2025) does not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (therapeutic tar anti-dandruff Anti-dandruff, anti-seborrheic dermatitis, anti-psoriasis), GOODSENSE, effective December 8, 2025 (SPL set 72ab0e6b-72a5-4e8a-af44-963251b0641f), via openFDA; the full label on DailyMed

What does the cyclosporine label say about coal tar?

Cyclosporine label, boxed warning

For Psoriasis Patients (see also BOXED WARNING above) Psoriasis patients previously treated with PUVA and to a lesser extent, methotrexate or other immunosuppressive agents, UVB, coal tar, or radiation therapy, are at an increased risk of developing skin malignancies when taking Neoral.

Cyclosporine label, contraindications

Psoriasis Psoriasis patients who are treated with Neoral should not receive concomitant PUVA or UVB therapy, methotrexate or other immunosuppressive agents, coal tar or radiation therapy.

Cyclosporine label, warnings

UVB and coal tar had been used by 2 and 3 patients, respectively.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Coal tar generic labelers
14Cyclosporine generic labelers
Coal tarCyclosporine
Labeled forPsoriasisOrgan transplant rejection, Rheumatoid arthritis
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0088 per mL 0.5% shampoo$1.04 per unit 0.05% eye emulsion
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?