What the FDA labels say about taking them together
Clorazepate and fosamprenavir
Fosamprenavir's FDA label of September 15, 2023 names clorazepate in its drug interactions section; the clorazepate label PlainMeds reads does not name fosamprenavir. The fosamprenavir label: “Clinical significance is unknown. A decrease in benzodiazepine dose may be needed.”
Check it at the source: the clorazepate FDA label on DailyMed (effective September 10, 2026, Apotex Corp.); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).
What does the clorazepate label say about fosamprenavir?
Clorazepate's label (effective September 10, 2026) does not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Clorazepate Dipotassium), ANDA215566 (Corepharma), as published by Apotex Corp., effective September 10, 2026 (SPL set 6e07efe5-29b6-6d1e-661a-f696c4b17f43), via openFDA; the full label on DailyMed
What does the fosamprenavir label say about clorazepate?
Fosamprenavir label, drug interactionsConcomitant Drug Class/Drug Name: Benzodiazepines: Alprazolam, clorazepate, diazepam, flurazepam; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Benzodiazepines; Clinical Comment: Clinical significance is unknown. A decrease in benzodiazepine dose may be needed.
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clorazepate | Fosamprenavir | |
|---|---|---|
| Labeled for | Anxiety, Seizures and epilepsy | HIV |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.524 per tablet 3.75 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once