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What the FDA labels say about taking them together

Clopidogrel and stiripentol

Stiripentol's FDA label of April 27, 2026 names clopidogrel in its drug interactions section; the clopidogrel label PlainMeds reads does not name stiripentol. The stiripentol label: “Because of potential inhibition of enzyme/transporter activity, consider a reduction in dosage of substrates of CYP2C8, CYP2C19, P-gp (e.g., carbamazepine), and BCRP, if adverse reactions are experienced when …”

Check it at the source: the clopidogrel FDA label on DailyMed (effective May 30, 2025, Sanofi-Aventis U.S. LLC); the stiripentol FDA label on DailyMed (effective April 27, 2026, BIOCODEX, INC.).

What does the clopidogrel label say about stiripentol?

Clopidogrel's label (effective May 30, 2025) does not name stiripentol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Plavix), Sanofi-Aventis U.S. LLC, effective May 30, 2025 (SPL set de8b0b67-eb25-4684-83b5-7ad785314227), via openFDA; the full label on DailyMed

What does the stiripentol label say about clopidogrel?

Stiripentol label, drug interactions

Because of potential inhibition of enzyme/transporter activity, consider a reduction in dosage of substrates of CYP2C8, CYP2C19 (e.g., diazepam, clopidogrel), P-gp (e.g., carbamazepine), and BCRP (e.g., methotrexate, prazosin, glyburide), if adverse reactions are experienced when administered concomitantly with DIACOMIT.

Source: FDA drug label (Diacomit), BIOCODEX, INC., effective April 27, 2026 (SPL set 58304ba8-9779-4658-811e-94ffe08c3f16), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

35Clopidogrel generic labelers
0Stiripentol generic labelers
ClopidogrelStiripentol
Labeled forHeart attack and coronary artery disease, Anginan/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0472 per tablet 75 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?