What the FDA labels say about taking them together
Clopidogrel and etravirine
Etravirine's FDA label of August 15, 2023 names clopidogrel in its drug interactions section; the clopidogrel label PlainMeds reads does not name etravirine. The etravirine label: “Activation of clopidogrel to its active metabolite may be decreased when clopidogrel is co-administered with INTELENCE. Alternatives to clopidogrel should be considered.”
Check it at the source: the clopidogrel FDA label on DailyMed (effective May 30, 2025, Sanofi-Aventis U.S. LLC); the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP).
What does the clopidogrel label say about etravirine?
Clopidogrel's label (effective May 30, 2025) does not name etravirine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Plavix), Sanofi-Aventis U.S. LLC, effective May 30, 2025 (SPL set de8b0b67-eb25-4684-83b5-7ad785314227), via openFDA; the full label on DailyMed
What does the etravirine label say about clopidogrel?
Etravirine label, drug interactionsConcomitant Drug Class/Drug Name: Platelet aggregation inhibitors: clopidogrel; Effect on Concentration of Etravirine or Concomitant Drug: ↓ clopidogrel (active) metabolite; Clinical Comment: Activation of clopidogrel to its active metabolite may be decreased when clopidogrel is co-administered with INTELENCE. Alternatives to clopidogrel should be considered.
Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clopidogrel | Etravirine | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease, Angina | HIV |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0472 per tablet 75 mg tablet | $9.94 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once