What the FDA labels say about taking them together
Clonidine and macimorelin
Macimorelin's FDA label of February 18, 2026 names clonidine in its drug interactions section; the clonidine labels PlainMeds reads (4) do not name macimorelin. The macimorelin label: “Drugs that may transiently elevate growth hormone concentrations.”
Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the macimorelin FDA label on DailyMed (effective February 18, 2026, Aeterna Zentaris GmbH).
What does the clonidine label say about macimorelin?
Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name macimorelin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
What does the macimorelin label say about clonidine?
Macimorelin label, drug interactionsDrugs that may transiently elevate growth hormone concentrations (such as clonidine, levodopa, and insulin).
Source: FDA drug label (Macrilen), Aeterna Zentaris GmbH, effective February 18, 2026 (SPL set aeb30f1a-4815-47ae-a2cb-b6b4e26372e1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clonidine | Macimorelin | |
|---|---|---|
| Labeled for | High blood pressure, ADHD, Pain | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0241 per tablet 0.1 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once