What the FDA labels say about taking them together
Clonidine and glipizide
Glipizide's FDA label of January 8, 2026 names clonidine in its drug interactions section; the clonidine labels PlainMeds reads (4) do not name glipizide.
Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited).
What does the clonidine label say about glipizide?
Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name glipizide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
What does the glipizide label say about clonidine?
Glipizide label, drug interactionsAlcohol, beta-blockers, clonidine, and reserpine may lead to either potentiation or weakening of the glucose-lowering effect.
Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clonidine | Glipizide | |
|---|---|---|
| Labeled for | High blood pressure, ADHD, Pain | Type 2 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0241 per tablet 0.1 mg tablet | $0.0339 per tablet 5 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once