What the FDA labels say about taking them together
Clobazam and fenfluramine
Fenfluramine's FDA label of October 27, 2025 names clobazam in its drug interactions section; the clobazam labels PlainMeds reads (2) do not name fenfluramine. The fenfluramine label: “DRUG INTERACTIONS Dose adjustment is required for patients taking stiripentol plus clobazam. Strong CYP1A2 or CYP2D6 inhibitors: a dose adjustment is recommended Strong CYP1A2, CYP2B6, or CYP3A4 inducers: it is …”
Check it at the source: the clobazam FDA label on DailyMed (effective March 12, 2024, Lundbeck Pharmaceuticals LLC); the fenfluramine FDA label on DailyMed (effective October 27, 2025, UCB, Inc.).
What does the clobazam label say about fenfluramine?
Clobazam's label (effective March 12, 2024) and its 1 other brand-application label do not name fenfluramine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Onfi), Lundbeck Pharmaceuticals LLC, effective March 12, 2024 (SPL set de03bd69-2dca-459c-93b4-541fd3e9571c), via openFDA; the full label on DailyMed
What does the fenfluramine label say about clobazam?
Fenfluramine label, drug interactionsDRUG INTERACTIONS Dose adjustment is required for patients taking stiripentol plus clobazam. ( 2.2 , 2.3 , 7.1 ) Strong CYP1A2 or CYP2D6 inhibitors: a dose adjustment is recommended ( 2.3 , 7.1 ) Strong CYP1A2, CYP2B6, or CYP3A4 inducers: it is recommended to avoid coadministration with FINTEPLA.
Source: FDA drug label (Fintepla), NDA212102 (Ucb Inc), as published by UCB, Inc., effective October 27, 2025 (SPL set e88f360e-33ad-4cd6-b2de-5ef885857c5d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clobazam | Fenfluramine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.243 per tablet 10 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once