What the FDA labels say about taking them together
Clindamycin and lincomycin
Clindamycin's FDA label of March 10, 2026 names lincomycin in its contraindications section, and lincomycin's label names clindamycin too. The lincomycin label: “CONTRAINDICATIONS LINCOCIN is contraindicated in patients previously found to be hypersensitive to lincomycin or clindamycin.”
Check it at the source: the clindamycin FDA label on DailyMed (effective March 10, 2026, GLENMARK PHARMACEUTICALS INC., USA); the lincomycin FDA label on DailyMed (effective March 10, 2025, Pharmacia & Upjohn Company LLC).
What does the clindamycin label say about lincomycin?
Clindamycin label, contraindicationsCONTRAINDICATIONS Clindamycin hydrochloride capsules are contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.
Xaciato label (Organon LLC, February 19, 2026), contraindicationsCONTRAINDICATIONS History of hypersensitivity to clindamycin or lincomycin.
Source: FDA drug label (Clindamycin Phosphate, NDA208083), Baxter Healthcare Company, effective April 28, 2026 (SPL set 44fa506b-90ac-42de-831b-5f3f1a500fc0), via openFDA
Source: FDA drug label (Xaciato, NDA215650), Organon LLC, effective February 19, 2026 (SPL set 0423007f-28fa-4159-bf58-9174626d2347), via openFDA
Source: FDA drug label (Clindamycin Hydrochloride), GLENMARK PHARMACEUTICALS INC., USA, effective March 10, 2026 (SPL set 8e66de7a-d9d4-4562-bc99-80489d482da4), via openFDA; the full label on DailyMed
What does the lincomycin label say about clindamycin?
Lincomycin label, contraindicationsCONTRAINDICATIONS LINCOCIN is contraindicated in patients previously found to be hypersensitive to lincomycin or clindamycin.
Source: FDA drug label (Lincocin), NDA050317 (Pfizer), as published by Pharmacia & Upjohn Company LLC, effective March 10, 2025 (SPL set c01906fa-2c73-4c13-9765-2fd06628d263), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clindamycin | Lincomycin | |
|---|---|---|
| Labeled for | Bacterial infections, Acne | Bacterial infections |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.137 per gram 1% gel | n/a |
| Shortage now | In shortage | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once