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What the FDA labels say about taking them together

Clarithromycin and vinblastine

Clarithromycin's FDA label of April 9, 2026 names vinblastine in its drug interactions section; the vinblastine label PlainMeds reads does not name clarithromycin.

Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the vinblastine FDA label on DailyMed (effective April 15, 2025, Fresenius Kabi USA, LLC).

What does the clarithromycin label say about vinblastine?

Clarithromycin label, drug interactions

Other Drugs Metabolized by CYP3A: Alfentanil Bromocriptine Cilostazol Methylprednisole Vinblastine Phenobarbital St. John’s Wort Use With Caution There have been spontaneous or published reports of CYP3A based interactions of clarithromycin with alfentanil, methylprednisolone, cilostazol, bromocriptine, vinblastine, phenobarbital, and St. John’s Wort.

Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed

What does the vinblastine label say about clarithromycin?

Vinblastine's label (effective April 15, 2025) does not name clarithromycin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Vinblastine Sulfate), Fresenius Kabi USA, LLC, effective April 15, 2025 (SPL set f073b58e-56d6-4c8d-a2ce-b37719402d77), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

26Clarithromycin generic labelers
1Vinblastine generic labelers
ClarithromycinVinblastine
Labeled forBacterial infections, Acid reflux and ulcersLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)$0.466 per tablet 500 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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