Skip to main content

What the FDA labels say about taking them together

Clarithromycin and ubrogepant

Ubrogepant's FDA label of June 5, 2025 names clarithromycin in its drug interactions section; the clarithromycin label PlainMeds reads does not name ubrogepant.

Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the ubrogepant FDA label on DailyMed (effective June 5, 2025, Allergan, Inc.).

What does the clarithromycin label say about ubrogepant?

Clarithromycin's label (effective April 9, 2026) does not name ubrogepant in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed

What does the ubrogepant label say about clarithromycin?

Ubrogepant label, drug interactions

UBRELVY should not be used with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin) [see Contraindication s ( 4 )].

Source: FDA drug label (UBRELVY), NDA211765 (Abbvie), as published by Allergan, Inc., effective June 5, 2025 (SPL set fd9f9458-fd96-4688-be3f-f77b3d1af6ab), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

26Clarithromycin generic labelers
0Ubrogepant generic labelers
ClarithromycinUbrogepant
Labeled forBacterial infections, Acid reflux and ulcersMigraine
Boxed warningNoNo
Pharmacy cost (NADAC)$0.466 per tablet 500 mg tablet$109.11 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?