What the FDA labels say about taking them together
Clarithromycin and talazoparib
Talazoparib's FDA label of April 10, 2026 names clarithromycin in its drug interactions section; the clarithromycin label PlainMeds reads does not name talazoparib. The talazoparib label: “Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.”
Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the talazoparib FDA label on DailyMed (effective April 10, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the clarithromycin label say about talazoparib?
Clarithromycin's label (effective April 9, 2026) does not name talazoparib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed
What does the talazoparib label say about clarithromycin?
Talazoparib label, drug interactionsDrugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.
Source: FDA drug label (Talzenna), Pfizer Laboratories Div Pfizer Inc, effective April 10, 2026 (SPL set c6fd147f-a77e-4a0b-9280-e82ecc41b4be), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clarithromycin | Talazoparib | |
|---|---|---|
| Labeled for | Bacterial infections, Acid reflux and ulcers | Breast cancer, Prostate cancer |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.466 per tablet 500 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once