Clarithromycin · more major-labeled pairs than Repaglinide
SPL labels Clarithromycin + Repaglinide as major; Clarithromycin 16 / Repaglinide 2 in that band.
Mechanism on file: Clarithromycin interferes with the enzyme that processes repaglinide, which can cause the medicine to stay in your system longer and drop your blood sugar too low.
FDA SPL severity: Major
Clarithromycin + Repaglinide · SPL mechanism field
Clarithromycin interferes with the enzyme that processes repaglinide, which can cause the medicine to stay in your system longer and drop your blood sugar too low.
Major band excerpt · Clarithromycin with Repaglinide
Gastroprokinetic Agents: Cisapride Contraindicated Cisapride: [See Contraindications ( 4.2 )] Lipid-lowering agents: Lomitapide Lovastatin Simvastatin Contraindicated Lomitapide, Lovastatin, Simvastatin: Clarithromycin may increase the exposure of these drugs by inhibition of CYP3A metabolism, thereby increasing the risk of toxicities from these drugs [see Contraindications ( 4.5 ) and Warnings and Precautions ( 5.4 )] Atorvastatin, Pravastatin, Fluvastatin: [See Warnings and Precautions ( 5.4 )] Atorvastatin Pravastatin Use With Caution Fluvastatin No Dose Adjustment Hypoglycemic Agents:...
Clarithromycin · 16 major-labeled pairs (vs Repaglinide's 2)
- Atorvastatin major
- Colchicine major
- Cyclosporine major
- Dronedarone major
Repaglinide · 2 major + 22 total pairs
- Gemfibrozil major
- Albuterol minor
- Clonidine moderate
- Clopidogrel minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.