What the FDA labels say about taking them together
Clarithromycin and deflazacort
Deflazacort's FDA label of November 13, 2025 names clarithromycin in its drug interactions section; the clarithromycin label PlainMeds reads does not name deflazacort. The deflazacort label: “Co-administration of deflazacort with clarithromycin, a strong CYP3A4 inhibitor, increased total exposure to 21-desDFZ by about 3-fold.”
Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the deflazacort FDA label on DailyMed (effective November 13, 2025, PTC Therapeutics, Inc.).
What does the clarithromycin label say about deflazacort?
Clarithromycin's label (effective April 9, 2026) does not name deflazacort in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed
What does the deflazacort label say about clarithromycin?
Deflazacort label, drug interactionsCo-administration of deflazacort with clarithromycin, a strong CYP3A4 inhibitor, increased total exposure to 21-desDFZ by about 3-fold.
Source: FDA drug label (EMFLAZA), PTC Therapeutics, Inc., effective November 13, 2025 (SPL set 31b347d2-f156-4055-9d8f-7cf0df420296), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clarithromycin | Deflazacort | |
|---|---|---|
| Labeled for | Bacterial infections, Acid reflux and ulcers | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.466 per tablet 500 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once