Clarithromycin · more major-labeled pairs than Aripiprazole
SPL labels Clarithromycin + Aripiprazole as minor; Clarithromycin 30 / Aripiprazole 19 in that band.
Mechanism on file: Clarithromycin slows down the liver's ability to process aripiprazole. This can lead to higher levels of aripiprazole in your blood, increasing the risk of side effects.
FDA SPL severity: Minor
Clarithromycin + Aripiprazole · SPL mechanism field
Clarithromycin slows down the liver's ability to process aripiprazole. This can lead to higher levels of aripiprazole in your blood, increasing the risk of side effects.
Minor band excerpt · Clarithromycin with Aripiprazole
7 DRUG INTERACTIONS Dosage adjustment due to drug interactions (7.1): Factors Dosage Adjustments for Aripiprazole Known CYP2D6 Poor Metabolizers Administer half of usual dose Known CYP2D6 Poor Metabolizers and strong CYP3A4 inhibitors Administer a quarter of usual dose Strong CYP2D6 or CYP3A4 inhibitors Administer half of usual dose Strong CYP2D6 and CYP3A4 inhibitors Administer a quarter of usual dose Strong CYP3A4 inducers Double usual dose over 1 to 2 weeks 7.1 Drugs Having Clinically Important Interactions with Aripiprazole Table 25: Clinically Important Drug Interactions with...
Clarithromycin · 16 major-labeled pairs (vs Aripiprazole's 0)
- Amlodipine minor
- Apixaban minor
- Carbamazepine minor
- Dabigatran minor
Aripiprazole · 19 minor + 19 total pairs
- Carbamazepine minor
- Desvenlafaxine minor
- Dextromethorphan minor
- Escitalopram minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.