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What the FDA labels say about taking them together

Citalopram and procainamide

Citalopram's FDA label of October 9, 2023 names procainamide in its warnings and precautions section; the procainamide label PlainMeds reads does not name citalopram.

Check it at the source: the citalopram FDA label on DailyMed (effective October 9, 2023, Allergan, Inc.); the procainamide FDA label on DailyMed (effective February 17, 2025, Caplin Steriles Limited).

What does the citalopram label say about procainamide?

Citalopram label, warnings and precautions

Such drugs include Class 1A (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications, antipsychotic medications (e.g., chlorpromazine, thioridazine), antibiotics (e.g., gatifloxacin, moxifloxacin), or any other class of medications known to prolong the QTc interval (e.g., pentamidine, levomethadyl acetate, methadone).

Source: FDA drug label (Celexa), NDA020822 (Abbvie), as published by Allergan, Inc., effective October 9, 2023 (SPL set 4259d9b1-de34-43a4-85a8-41dd214e9177), via openFDA; the full label on DailyMed

What does the procainamide label say about citalopram?

Procainamide's label (effective February 17, 2025) does not name citalopram in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Procainamide Hydrochloride), Caplin Steriles Limited, effective February 17, 2025 (SPL set fcaa5e9a-3c8a-4796-aa87-626268b6cf60), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

35Citalopram generic labelers
11Procainamide generic labelers
CitalopramProcainamide
Labeled forDepressionn/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.026 per tablet 10 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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