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What the FDA labels say about taking them together

Cisplatin and ondansetron

Ondansetron's FDA label of January 8, 2026 names cisplatin in its drug interactions section; the cisplatin label PlainMeds reads does not name ondansetron. The ondansetron label: “Chemotherapy Carmustine, etoposide, and cisplatin do not affect the pharmacokinetics of ondansetron.”

Check it at the source: the cisplatin FDA label on DailyMed (effective September 16, 2021, WG Critical Care, LLC); the ondansetron FDA label on DailyMed (effective January 8, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the cisplatin label say about ondansetron?

Cisplatin's label (effective September 16, 2021) does not name ondansetron in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CISplatin), NDA018057 (Hq Spclt Pharma), as published by WG Critical Care, LLC, effective September 16, 2021 (SPL set 2bf8d2fb-80c8-401d-8e9b-d58463f5e954), via openFDA; the full label on DailyMed

What does the ondansetron label say about cisplatin?

Ondansetron label, drug interactions

Chemotherapy Carmustine, etoposide, and cisplatin do not affect the pharmacokinetics of ondansetron.

Source: FDA drug label (Ondansetron), Glenmark Pharmaceuticals Inc., USA, effective January 8, 2026 (SPL set eee5217a-eba8-463a-812d-bf3c66f0934f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Cisplatin generic labelers
77Ondansetron generic labelers
CisplatinOndansetron
Labeled forn/aNausea and vomiting
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$0.0582 per tablet 4 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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