What the FDA labels say about taking them together
Cisplatin and neomycin
Neomycin's FDA label of February 12, 2026 names cisplatin in its boxed warning (prescription label) section; the cisplatin label PlainMeds reads does not name neomycin. The neomycin label: “… other potentially nephrotoxic and/or neurotoxic drugs such as bacitracin, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin and viomycin, should be avoided because the toxicity may be additive.”
Check it at the source: the cisplatin FDA label on DailyMed (effective September 16, 2021, WG Critical Care, LLC); the neomycin FDA label on DailyMed (effective February 12, 2026).
What does the cisplatin label say about neomycin?
Cisplatin's label (effective September 16, 2021) does not name neomycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CISplatin), NDA018057 (Hq Spclt Pharma), as published by WG Critical Care, LLC, effective September 16, 2021 (SPL set 2bf8d2fb-80c8-401d-8e9b-d58463f5e954), via openFDA; the full label on DailyMed
What does the neomycin label say about cisplatin?
Neomycin label, boxed warning (prescription label)Concurrent and/or sequential systemic, oral or topical use of other aminoglycosides, including paromomycin and other potentially nephrotoxic and/or neurotoxic drugs such as bacitracin, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin and viomycin, should be avoided because the toxicity may be additive.
Source: FDA drug label (Neomycin Sulfate), Aldermed Inc., effective February 12, 2026 (SPL set 4978bb06-8b7c-9a44-e063-6294a90ac4cf), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cisplatin | Neomycin | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.833 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once