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What the FDA labels say about taking them together

Cisplatin and ifosfamide

Ifosfamide's FDA label of December 2, 2024 names cisplatin in its warnings and precautions section; the cisplatin label PlainMeds reads does not name ifosfamide. The ifosfamide label: “… status, bulky abdominal-pelvic disease, nephrotoxic treatments including cisplatin, CNS active drugs, or alcohol use.”

Check it at the source: the cisplatin FDA label on DailyMed (effective September 16, 2021, WG Critical Care, LLC); the ifosfamide FDA label on DailyMed (effective December 2, 2024).

What does the cisplatin label say about ifosfamide?

Cisplatin's label (effective September 16, 2021) does not name ifosfamide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CISplatin), NDA018057 (Hq Spclt Pharma), as published by WG Critical Care, LLC, effective September 16, 2021 (SPL set 2bf8d2fb-80c8-401d-8e9b-d58463f5e954), via openFDA; the full label on DailyMed

What does the ifosfamide label say about cisplatin?

Ifosfamide label, warnings and precautions

Risk factors include high ifosfamide dosage, hypoalbuminemia, impaired renal function, poor performance status, bulky abdominal-pelvic disease, nephrotoxic treatments including cisplatin, CNS active drugs, or alcohol use.

Source: FDA drug label (IFEX), Baxter Healthcare Corporation, effective December 2, 2024 (SPL set b7241707-7538-4d1a-91e7-3a25a91e0b9a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Cisplatin generic labelers
2Ifosfamide generic labelers
CisplatinIfosfamide
Labeled forn/an/a
Boxed warningYesYes
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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