What the FDA labels say about taking them together
Cinacalcet and ketoconazole
Cinacalcet's FDA label of April 2, 2026 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name cinacalcet. The cinacalcet label: “Dose adjustment of Sensipar may be required if a patient initiates or discontinues therapy with a strong CYP3A4 inhibitor.”
Check it at the source: the cinacalcet FDA label on DailyMed (effective April 2, 2026, Aurobindo Pharma Limited); the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).
What does the cinacalcet label say about ketoconazole?
Cinacalcet label, drug interactionsDose adjustment of cinacalcet may be required if a patient initiates or discontinues therapy with a strong CYP3A4 inhibitor (e.g., ketoconazole, itraconazole).
Source: FDA drug label (Sensipar, NDA021688), Amgen Inc, effective December 7, 2025 (SPL set 45028573-13c4-4c8b-ae62-6c75bba97c81), via openFDA
Source: FDA drug label (Cinacalcet), Aurobindo Pharma Limited, effective April 2, 2026 (SPL set 200390f2-7dad-4ecc-a086-c29e18525c01), via openFDA; the full label on DailyMed
What does the ketoconazole label say about cinacalcet?
Ketoconazole's label (effective January 28, 2026) does not name cinacalcet in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cinacalcet | Ketoconazole | |
|---|---|---|
| Labeled for | n/a | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.411 per tablet 30 mg tablet | $0.249 per gram 2% cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once