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What the FDA labels say about taking them together

Cimetidine and thalidomide

Thalidomide's FDA label of March 24, 2023 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name thalidomide.

Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).

What does the cimetidine label say about thalidomide?

Cimetidine's label (effective July 15, 2026) does not name thalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed

What does the thalidomide label say about cimetidine?

Thalidomide label, drug interactions

Non-cardiac drugs that may cause bradycardia include H2 blockers (e.g., famotidine, cimetidine), lithium, tricyclic antidepressants and neuromuscular blockers (succinylcholine).

Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Cimetidine generic labelers
0Thalidomide generic labelers
CimetidineThalidomide
Labeled forAcid reflux and ulcersLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)$0.236 per tablet 300 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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