What the FDA labels say about taking them together
Cimetidine and nisoldipine
Nisoldipine's FDA label of March 12, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name nisoldipine. The nisoldipine label: “Drug Interactions A 30 to 45% increase in AUC and C max of nisoldipine was observed with concomitant administration of cimetidine 400 mg twice daily.”
Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the nisoldipine FDA label on DailyMed (effective March 12, 2026, Covis Pharma US, Inc).
What does the cimetidine label say about nisoldipine?
Cimetidine's label (effective July 15, 2026) does not name nisoldipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
What does the nisoldipine label say about cimetidine?
Nisoldipine label, drug interactionsDrug Interactions A 30 to 45% increase in AUC and C max of nisoldipine was observed with concomitant administration of cimetidine 400 mg twice daily.
Source: FDA drug label (Sular), NDA020356 (Azurity), as published by Covis Pharma US, Inc, effective March 12, 2026 (SPL set 589157fa-d129-4de3-be3d-e0e1c22c5873), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cimetidine | Nisoldipine | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.236 per tablet 300 mg tablet | $5.24 per tablet 34 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once