What the FDA labels say about taking them together
Cimetidine and fluvastatin
Fluvastatin's FDA label of April 21, 2025 names cimetidine in its warnings and precautions section; the cimetidine label PlainMeds reads does not name fluvastatin. The fluvastatin label: “Caution should be exercised if a statin or other agent used to lower cholesterol levels is administered to patients receiving other drugs that may decrease the levels of endogenous steroid hormones.”
Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the fluvastatin FDA label on DailyMed (effective April 21, 2025, Teva Pharmaceuticals USA, Inc.).
What does the cimetidine label say about fluvastatin?
Cimetidine's label (effective July 15, 2026) does not name fluvastatin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
What does the fluvastatin label say about cimetidine?
Fluvastatin label, warnings and precautionsCaution should be exercised if a statin or other agent used to lower cholesterol levels is administered to patients receiving other drugs (e.g., ketoconazole, spironolactone, cimetidine) that may decrease the levels of endogenous steroid hormones.
Source: FDA drug label (Fluvastatin), Teva Pharmaceuticals USA, Inc., effective April 21, 2025 (SPL set aad8b373-0aec-4efb-8e61-3d8114b31127), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cimetidine | Fluvastatin | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | High cholesterol |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.236 per tablet 300 mg tablet | $2.88 per tablet 80 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once