What the FDA labels say about taking them together
Cimetidine and flibanserin
Flibanserin's FDA label of December 22, 2025 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name flibanserin. The flibanserin label: “Multiple Concomitant Weak CYP3A4 Inhibitors Concomitant use of multiple weak CYP3A4 inhibitors that may include herbal supplements or non-prescription drugs (e.g., cimetidine) could also lead to clinically relevant …”
Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the flibanserin FDA label on DailyMed (effective December 22, 2025, Sprout Pharmaceuticals, Inc.).
What does the cimetidine label say about flibanserin?
Cimetidine's label (effective July 15, 2026) does not name flibanserin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
What does the flibanserin label say about cimetidine?
Flibanserin label, drug interactionsExamples; Oral contraceptives, cimetidine, fluoxetine, ginkgo, ranitidine
Flibanserin label, warnings and precautionsMultiple Concomitant Weak CYP3A4 Inhibitors Concomitant use of multiple weak CYP3A4 inhibitors that may include herbal supplements (e.g., ginkgo, resveratrol) or non-prescription drugs (e.g., cimetidine) could also lead to clinically relevant increases in flibanserin concentrations that may increase the risk of hypotension and syncope [see Drug Interactions (7) ].
Source: FDA drug label (ADDYI), Sprout Pharmaceuticals, Inc., effective December 22, 2025 (SPL set 3819daf3-e935-2c53-c527-e1d57922f394), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cimetidine | Flibanserin | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.236 per tablet 300 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once