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What the FDA labels say about taking them together

Cimetidine and epirubicin

Epirubicin's FDA label of July 24, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name epirubicin. The epirubicin label: “Cimetidine increases the exposure to epirubicin.”

Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the epirubicin FDA label on DailyMed (effective July 24, 2026, Pharmacia & Upjohn Company LLC).

What does the cimetidine label say about epirubicin?

Cimetidine's label (effective July 15, 2026) does not name epirubicin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed

What does the epirubicin label say about cimetidine?

Epirubicin label, drug interactions

Cimetidine increases the exposure to epirubicin [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (Ellence), NDA050778 (Pfizer Inc), as published by Pharmacia & Upjohn Company LLC, effective July 24, 2026 (SPL set 0a03c798-a652-4895-b29c-3b521a89ba42), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Cimetidine generic labelers
0Epirubicin generic labelers
CimetidineEpirubicin
Labeled forAcid reflux and ulcersn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.236 per tablet 300 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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