What the FDA labels say about taking them together
Cilostazol and omeprazole
Cilostazol's FDA label of September 10, 2026 names omeprazole in its drug interactions section, and omeprazole's label names cilostazol too. The omeprazole label: “Increased exposure of one of the active metabolites of cilostazol (3,4-dihydro-cilostazol).”
Check it at the source: the cilostazol FDA label on DailyMed (effective September 10, 2026, Apotex Corp.); the omeprazole FDA label on DailyMed (effective April 22, 2024, Apotex Corp).
What does the cilostazol label say about omeprazole?
Cilostazol label, drug interactionsInhibitors of CYP2C19 Coadministration with CYP2C19 inhibitors (e.g., omeprazole) increases systemic exposure of cilostazol active metabolites.
Source: FDA drug label (cilostazol), Apotex Corp., effective September 10, 2026 (SPL set ceac1ae3-c343-28ca-c083-b748d21a15e6), via openFDA; the full label on DailyMed
What does the omeprazole label say about cilostazol?
Omeprazole label, drug interactionsCilostazol Clinical Impact: Increased exposure of one of the active metabolites of cilostazol (3,4-dihydro-cilostazol). Intervention: Reduce the dose of cilostazol to 50 mg twice daily. See prescribing information for cilostazol.
Source: FDA drug label (Omeprazole), Apotex Corp, effective April 22, 2024 (SPL set b83329ac-a65e-b3af-a3fb-c5a6c740e5e7), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cilostazol | Omeprazole | |
|---|---|---|
| Labeled for | n/a | Acid reflux and ulcers |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.132 per tablet 100 mg tablet | $0.0295 per capsule 20 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once