What the FDA labels say about taking them together
Ciclesonide and ritonavir
Ritonavir's FDA label of July 23, 2026 names ciclesonide in its drug interactions section; the ciclesonide labels PlainMeds reads (2) do not name ritonavir. The ritonavir label: “Coadministration with corticosteroids whose exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing’s syndrome and adrenal suppression.Alternative corticosteroids including …”
Check it at the source: the ciclesonide FDA label on DailyMed (effective February 28, 2025, Covis Pharma US, Inc); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the ciclesonide label say about ritonavir?
Ciclesonide's label (effective February 28, 2025) and its 1 other brand-application label do not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Alvesco), NDA021658 (Azurity), as published by Covis Pharma US, Inc, effective February 28, 2025 (SPL set 9f6112fb-78ef-43cf-8ae3-36370eb45468), via openFDA; the full label on DailyMed
What does the ritonavir label say about ciclesonide?
Ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Systemic/Inhaled/ Nasal/Ophthalmic Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ glucocorticoids; Clinical Comment: Coadministration with corticosteroids whose exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing’s syndrome and adrenal suppression.Alternative corticosteroids including beclomethasone and prednisolone (whose PK and/or PD are less affected by strong CYP3A inhibitors relative to other studied steroids) should be considered, particularly for …
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ciclesonide | Ritonavir | |
|---|---|---|
| Labeled for | Asthma, Allergies | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $42.97 per gram 160 mcg inhaler | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once